The eight buildings were awarded heritage status by at a meeting on July 7 in Baku, Azerbaijan.
Alongside the Guggenheim Museum and Fallingwater, the six other listed sites are Frederick C Robie House, Illinois, Hollyhock House, California, the Herbert and Katherine Jacobs House, and Wisconsin, Unity Temple in Oak Park, along with Wright's homes and studios at Taliesin, Wisconsin, and Taliesin West, Arizona – both of which are now home to The School of Architecture at Taliesin.
Along with the eight Wright buildings, there are now 24 UNESCO World Heritage Sites in the US.
These buildings are the first pieces of modern architecture from the country to have been recognised by the international conservation body.
has been working with property owners and custodians for a decade and a half to have the 20th-century buildings officially recognised.
"This recognition by UNESCO is a significant way for us to reconfirm how important Frank Lloyd Wright was to the development of modern architecture around the world," said Barbara Gordon, executive director of the Frank Lloyd Wright Building Conservancy.
"There are nearly 400 remaining structures designed by Wright. Our hope is that the inscription of these eight major works also brings awareness to the importance of preserving all of his buildings as a vital part of our artistic, cultural and architectural heritage," she added.
A list of 10 buildings was originally submitted in 2015, but was revised down to eight works for the 2018 submission. Price Tower in Oklahoma and the Marin County Civic Center in California were the sites that didn't make the final list.
Wright is considered one of the most important architects working in the 20th century. He pioneered the Prairie School of architecture, a movement that sought to develop an "indigenous" style of American design.
In a career that spanned 70 years he designed landmark hotels, museums, churches and skyscrapers as well as private homes, often expanding his creative control beyond the title of architect to be an urban planner and interior designer. The MoMA staged a retrospective of his work to mark 150 years since his birth in 2017.
In 2016 UNESCO added 17 projects by 20th-century French architect Le Corbusier to its World Heritage List.
Main photo is by Carol M. Highsmith.